Oral Metastasis as the First Manifestation of an Extragonadal Primary Choriocarcinoma of Pancreas: A Rare Case Report

Incidences of metastatic tumor occurrences in the oral cavity are very rare and their participation is less than 1% of all the jaw tumors. About two-third of the total occurrences (65%) are derived from the primary lesions of breast, lungs, liver, kidney, pancreas and one-third oral metastases (35%) are derived from testicles, uterus, thyroid, colon, rectum, stomach and prostate. The commonly affected oral sites for metastases are gingiva, buccal mucosa, soft palate, tongue and jaw bones. Their occurrences are more common in mandible than in maxilla and are more predominantly seen in females. Among all oral metastases a metastatic lesion from a germinomatous or a nongerminomatous germ cell tumor is very unusual. Commonly these types of tumors are benign in nature, but occasionally they turned into carcinomatous lesions. An unusual case of oral manifestation of an extremely rare extragonadal nongerminomatous primary choriocarcinoma of pancreas, with secondaries in liver and lung, is described in this article.